Initial experience with fibrin sealant in pendulous urethral reconstruction. Is early catheter removal possible?

Eric J. Hick, Allen F. Morey

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Purpose: We assessed whether fibrin sealant promotes early catheter removal after pendulous urethral reconstruction. Materials and Methods: Between 1997 and 2003, 43 men with complex stricture disease underwent pendulous urethral reconstruction by a single surgeon (AFM). In 18 consecutive cases with a mean stricture length of 7.24 cm from 2000 to 2003 fibrin sealant was applied over a ventral onlay anastomosis performed with running 5-zero polydiaxanone suture. Results were compared with those in 25 men who underwent the procedure without fibrin sealant from 1997 to 2000, who served as a control group (mean stricture length 8.30 cm, p = 0.418). Catheter duration was recorded after anastomosis integrity was radiographically confirmed. Results: All 18 patients with sealant were completely healed within 14 days, which was significantly shorter than in controls (p <0.001). In the sealant group increased stricture length was associated with longer catheter time (p = 0.677). Our impressions were that patient satisfaction was enhanced by early catheter removal, and postoperative penile edema and ecchymosis were decreased in the fibrin sealant group. Conclusions: Fibrin sealant appears to promote early catheter removal and enhanced wound healing after pendulous urethral reconstruction.

Original languageEnglish (US)
Pages (from-to)1547-1549
Number of pages3
JournalJournal of Urology
Issue number4
StatePublished - Apr 2004


  • Catheterization
  • Fibrin tissue adhesive
  • Urethra
  • Urethral stricture

ASJC Scopus subject areas

  • Urology


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