Insulin and the burned patient

Heather F. Pidcoke, Charles E. Wade, Steven E. Wolf

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Severe burns lead to insulin resistance, which is associated with hyperglycemia and muscle wasting. Investigators showed relatively recently that control of hyperglycemia with intensive insulin treatment is associated with improved outcomes for those in the intensive care unit, including patients with severe burns. In this article, we review the actions of insulin in terms of glycemic control and muscle metabolism, biochemical and clinical effects of insulin treatment in the severely burned, and the vagaries of glucose control.

Original languageEnglish (US)
Pages (from-to)S524-S530
JournalCritical care medicine
Volume35
Issue number9 SUPPL.
DOIs
StatePublished - Sep 1 2007

Keywords

  • Burns
  • Glycemic control
  • Insulin resistance
  • Muscle metabolism
  • Muscle wasting

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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    Pidcoke, H. F., Wade, C. E., & Wolf, S. E. (2007). Insulin and the burned patient. Critical care medicine, 35(9 SUPPL.), S524-S530. https://doi.org/10.1097/01.CCM.0000278065.72486.31