Insulin second messengers: Synthesis of 6-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-chiro-inositol-1-phosphate

K. Kishta Reddy, J R Falck, Jorge Capdevila

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

An efficient enantiospecific route to protected chiro-inositol 7 from (-)-quinic acid was exploited for the synthesis of the title disaccharide which displayed insulin mimetic activity.

Original languageEnglish (US)
Pages (from-to)7869-7872
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number49
DOIs
StatePublished - Dec 3 1993

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Keywords

  • Chiro-inositol
  • PIM
  • inositol glycan
  • insulin mimetic
  • quinic acid

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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