Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes

Abdallah G. Rebeiz, Matthew T. Roe, John H. Alexander, Kenneth W. Mahaffey, Christopher B. Granger, Eric D. Peterson, Robert M. Califf, Robert A. Harrington

Research output: Contribution to journalReview articlepeer-review

Abstract

Non-ST-segment elevation acute coronary syndromes are a dramatic manifestation of coronary artery disease. Multiple clinical trials have shown that early cardiac catheterization improves clinical outcomes in patients with non-ST-segment elevation acute coronary syndromes. Many antithrombotic agents effectively manage unstable coronary syndromes and serve as adjuncts to percutaneous coronary intervention. Yet, the growing number of pharmacologic agents makes early management of non-ST-segment elevation acute coronary syndromes increasingly complex. We review the current evidence regarding the optimal integration of early antithrombotic and antiplatelet therapies with early coronary angiography and subsequent revascularization.

Original languageEnglish (US)
Pages (from-to)119-129
Number of pages11
JournalAmerican Journal of Medicine
Volume116
Issue number2
DOIs
StatePublished - Jan 15 2004
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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