Intentional delivery versus expectant management with preterm ruptured membranes at 30-34 weeks' gestation

S. M. Cox, K. J. Leveno

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

Objective: To determine maternal and neonatal outcomes in pregnancies complicated by preterm rupture of membranes (PROM) at 30-34 weeks' gestation. Methods: A randomized controlled trial was conducted to study the benefits of expectant management in women hospitalized for PROM at 30-34 weeks' gestation. During this investigation, no tocolytics, corticosteroids, or prophylactic antibiotics were used. Results: Sixty-eight women with PROM were managed expectantly and 61 were delivered intentionally. The mean gestational age at study entry was 31.7 weeks in both the expectant management and intentional delivery groups (P > .05). The mean gestational ages at delivery were similar (32.0 and 31.7 weeks, respectively). Other indices of pregnancy outcome (ie, birth weight, intraventricular hemorrhage, necrotizing enterocolitis, sepsis, respiratory distress syndrome, and perinatal death) were not significantly improved by expectant management. However, there was a significant increase in the incidence of chorioamnionitis and antepartum hospitalization in the women managed expectantly. Conclusion: There were no clinically significant neonatal advantages to expectant management of ruptured membranes at 30-34 weeks. Antepartum hospitalization was decreased by 2.5 days in those women randomized to intentional delivery.

Original languageEnglish (US)
Pages (from-to)875-879
Number of pages5
JournalObstetrics and Gynecology
Volume86
Issue number6
DOIs
StatePublished - 1995

Fingerprint

Rupture
Pregnancy
Membranes
Pregnancy Outcome
Gestational Age
Hospitalization
Tocolytic Agents
Chorioamnionitis
Necrotizing Enterocolitis
Birth Weight
Sepsis
Adrenal Cortex Hormones
Randomized Controlled Trials
Mothers
Hemorrhage
Anti-Bacterial Agents
Incidence
Perinatal Death

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Intentional delivery versus expectant management with preterm ruptured membranes at 30-34 weeks' gestation. / Cox, S. M.; Leveno, K. J.

In: Obstetrics and Gynecology, Vol. 86, No. 6, 1995, p. 875-879.

Research output: Contribution to journalArticle

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