Inter-kingdom signalling

Communication between bacteria and their hosts

David T. Hughes, Vanessa Sperandio

Research output: Contribution to journalArticle

392 Citations (Scopus)

Abstract

Microorganisms and their hosts communicate with each other through an array of hormonal signals. This cross-kingdom cell-to-cell signalling involves small molecules, such as hormones that are produced by eukaryotes and hormone-like chemicals that are produced by bacteria. Cell-to-cell signalling between bacteria, usually referred to as quorum sensing, was initially described as a means by which bacteria achieve signalling in microbial communities to coordinate gene expression within a population. Recent evidence shows, however, that quorum-sensing signalling is not restricted to bacterial cell-to-cell communication, but also allows communication between microorganisms and their hosts.

Original languageEnglish (US)
Pages (from-to)111-120
Number of pages10
JournalNature Reviews Microbiology
Volume6
Issue number2
DOIs
StatePublished - Feb 2008

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Bacteria
Quorum Sensing
Hormones
Eukaryota
Cell Communication
Gene Expression
Population

ASJC Scopus subject areas

  • Microbiology

Cite this

Inter-kingdom signalling : Communication between bacteria and their hosts. / Hughes, David T.; Sperandio, Vanessa.

In: Nature Reviews Microbiology, Vol. 6, No. 2, 02.2008, p. 111-120.

Research output: Contribution to journalArticle

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