Abstract
Bacteria have devised sophisticated His-Asp phosphorelay signaling systems for eliciting a variety of adaptive responses to their environment. The histidine-containing phosphotransfer (HPt) domain, found in many signal transduction protein, functions as a mediator of the His-Asp phosphorelay. The ArcB anaerobic sensor of E. coli contains such a HPt domain, although its function is not fully understood. In this study, we provide in vivo and in vitro evidence that the HPt domain is capable of interacting with the CheY receiver, which contains a phospho-accepting aspartate residue.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 337-340 |
| Number of pages | 4 |
| Journal | FEBS Letters |
| Volume | 408 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 26 1997 |
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Keywords
- ArcB anerobic sensor
- CheY response regulator
- HPt phosphotransfer domain
- Phosphotransfer signaling in E. coli
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology
Cite this
Interaction between the CheY response regulator and the histidine-containing phosphotransfer (HPt) domain of the ArcB sensory kinase in Escherichia coli. / Yaku, Hidenobu; Kato, Masato; Hakoshima, Toshio; Tsuzuki, Masakatsu; Mizuno, Takeshi.
In: FEBS Letters, Vol. 408, No. 3, 26.05.1997, p. 337-340.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interaction between the CheY response regulator and the histidine-containing phosphotransfer (HPt) domain of the ArcB sensory kinase in Escherichia coli
AU - Yaku, Hidenobu
AU - Kato, Masato
AU - Hakoshima, Toshio
AU - Tsuzuki, Masakatsu
AU - Mizuno, Takeshi
PY - 1997/5/26
Y1 - 1997/5/26
N2 - Bacteria have devised sophisticated His-Asp phosphorelay signaling systems for eliciting a variety of adaptive responses to their environment. The histidine-containing phosphotransfer (HPt) domain, found in many signal transduction protein, functions as a mediator of the His-Asp phosphorelay. The ArcB anaerobic sensor of E. coli contains such a HPt domain, although its function is not fully understood. In this study, we provide in vivo and in vitro evidence that the HPt domain is capable of interacting with the CheY receiver, which contains a phospho-accepting aspartate residue.
AB - Bacteria have devised sophisticated His-Asp phosphorelay signaling systems for eliciting a variety of adaptive responses to their environment. The histidine-containing phosphotransfer (HPt) domain, found in many signal transduction protein, functions as a mediator of the His-Asp phosphorelay. The ArcB anaerobic sensor of E. coli contains such a HPt domain, although its function is not fully understood. In this study, we provide in vivo and in vitro evidence that the HPt domain is capable of interacting with the CheY receiver, which contains a phospho-accepting aspartate residue.
KW - ArcB anerobic sensor
KW - CheY response regulator
KW - HPt phosphotransfer domain
KW - Phosphotransfer signaling in E. coli
UR - http://www.scopus.com/inward/record.url?scp=0031587037&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031587037&partnerID=8YFLogxK
U2 - 10.1016/S0014-5793(97)00459-6
DO - 10.1016/S0014-5793(97)00459-6
M3 - Article
C2 - 9188789
AN - SCOPUS:0031587037
VL - 408
SP - 337
EP - 340
JO - FEBS Letters
JF - FEBS Letters
SN - 0014-5793
IS - 3
ER -