Interferon: Status in treatment of skin disease

K. B. Yancey, J. G. Smith

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Interferons, glycoproteins originally investigated as antiviral agents, are now known to be active as anticancer agents, immune system modulators, and growth control regulators. For these reasons, interferons have definite and documented relevance to dermatologists. In regard to viral diseases, therapeutic trials in humans have shown promising results in herpes simplex infections, vaccinia, laryngeal papillomas, and condyloma acuminatum, as well as in rabies and hepatitis B. Pilot studies with interferon treatment of melanoma have been so promising that the American Cancer Society has selected this area to receive additional research support. Also, the antiproliferative effects of interferons have potential application to proliferative diseases such as psoriasis.

Original languageEnglish (US)
Pages (from-to)585-595
Number of pages11
JournalJournal of the American Academy of Dermatology
Volume3
Issue number6
StatePublished - 1980

Fingerprint

Skin Diseases
Interferons
Vaccinia
Condylomata Acuminata
Herpes Simplex
Rabies
Papilloma
Virus Diseases
Therapeutics
Hepatitis B
Psoriasis
Antineoplastic Agents
Antiviral Agents
Immune System
Melanoma
Glycoproteins
Growth
Infection

ASJC Scopus subject areas

  • Dermatology

Cite this

Interferon : Status in treatment of skin disease. / Yancey, K. B.; Smith, J. G.

In: Journal of the American Academy of Dermatology, Vol. 3, No. 6, 1980, p. 585-595.

Research output: Contribution to journalArticle

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