Interferon: Status in treatment of skin disease

K. B. Yancey, J. G. Smith

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Interferons, glycoproteins originally investigated as antiviral agents, are now known to be active as anticancer agents, immune system modulators, and growth control regulators. For these reasons, interferons have definite and documented relevance to dermatologists. In regard to viral diseases, therapeutic trials in humans have shown promising results in herpes simplex infections, vaccinia, laryngeal papillomas, and condyloma acuminatum, as well as in rabies and hepatitis B. Pilot studies with interferon treatment of melanoma have been so promising that the American Cancer Society has selected this area to receive additional research support. Also, the antiproliferative effects of interferons have potential application to proliferative diseases such as psoriasis.

Original languageEnglish (US)
Pages (from-to)585-595
Number of pages11
JournalJournal of the American Academy of Dermatology
Volume3
Issue number6
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Dermatology

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