Intestinal secretion as a cause of hypokalemia and cardiac arrest in a patient with Strongyloidiasis

Mary G. Kane, James P. Luby, Guenter J. Krejs

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A 32-year-old white American male contracted strongyloidiasis in Nigeria. Prolonged and severe watery diarrhea was complicated by hypokalemia and cardiac arrest. Steady-state perfusion studies with a plasma-like electrolyte solution revealed net secretion of water, sodium, potasssium, and chloride in a segment of jejunum. Mucosal permeability measured by the ration of [14C]urea and tritiated water diffusion was unchanged. Chloride secretion occurred against both an electrical and chemical gradient, which suggests that chloride secretion was active. Intestinal water and electrolyte secretion may be the mechanism of watery diarrhea in patients with strongyloidiasis.

Original languageEnglish (US)
Pages (from-to)768-772
Number of pages5
JournalDigestive Diseases and Sciences
Volume29
Issue number8
DOIs
StatePublished - Aug 1984

Fingerprint

Strongyloidiasis
Intestinal Secretions
Hypokalemia
Heart Arrest
Electrolytes
Water
Chlorides
Diarrhea
Jejunum
Nigeria
Sodium Chloride
Urea
Permeability
Perfusion

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Intestinal secretion as a cause of hypokalemia and cardiac arrest in a patient with Strongyloidiasis. / Kane, Mary G.; Luby, James P.; Krejs, Guenter J.

In: Digestive Diseases and Sciences, Vol. 29, No. 8, 08.1984, p. 768-772.

Research output: Contribution to journalArticle

@article{93cc3bd580414785b2bb6a6d0d711d05,
title = "Intestinal secretion as a cause of hypokalemia and cardiac arrest in a patient with Strongyloidiasis",
abstract = "A 32-year-old white American male contracted strongyloidiasis in Nigeria. Prolonged and severe watery diarrhea was complicated by hypokalemia and cardiac arrest. Steady-state perfusion studies with a plasma-like electrolyte solution revealed net secretion of water, sodium, potasssium, and chloride in a segment of jejunum. Mucosal permeability measured by the ration of [14C]urea and tritiated water diffusion was unchanged. Chloride secretion occurred against both an electrical and chemical gradient, which suggests that chloride secretion was active. Intestinal water and electrolyte secretion may be the mechanism of watery diarrhea in patients with strongyloidiasis.",
author = "Kane, {Mary G.} and Luby, {James P.} and Krejs, {Guenter J.}",
year = "1984",
month = "8",
doi = "10.1007/BF01312953",
language = "English (US)",
volume = "29",
pages = "768--772",
journal = "Digestive Diseases and Sciences",
issn = "0163-2116",
publisher = "Springer New York",
number = "8",

}

TY - JOUR

T1 - Intestinal secretion as a cause of hypokalemia and cardiac arrest in a patient with Strongyloidiasis

AU - Kane, Mary G.

AU - Luby, James P.

AU - Krejs, Guenter J.

PY - 1984/8

Y1 - 1984/8

N2 - A 32-year-old white American male contracted strongyloidiasis in Nigeria. Prolonged and severe watery diarrhea was complicated by hypokalemia and cardiac arrest. Steady-state perfusion studies with a plasma-like electrolyte solution revealed net secretion of water, sodium, potasssium, and chloride in a segment of jejunum. Mucosal permeability measured by the ration of [14C]urea and tritiated water diffusion was unchanged. Chloride secretion occurred against both an electrical and chemical gradient, which suggests that chloride secretion was active. Intestinal water and electrolyte secretion may be the mechanism of watery diarrhea in patients with strongyloidiasis.

AB - A 32-year-old white American male contracted strongyloidiasis in Nigeria. Prolonged and severe watery diarrhea was complicated by hypokalemia and cardiac arrest. Steady-state perfusion studies with a plasma-like electrolyte solution revealed net secretion of water, sodium, potasssium, and chloride in a segment of jejunum. Mucosal permeability measured by the ration of [14C]urea and tritiated water diffusion was unchanged. Chloride secretion occurred against both an electrical and chemical gradient, which suggests that chloride secretion was active. Intestinal water and electrolyte secretion may be the mechanism of watery diarrhea in patients with strongyloidiasis.

UR - http://www.scopus.com/inward/record.url?scp=0021153598&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021153598&partnerID=8YFLogxK

U2 - 10.1007/BF01312953

DO - 10.1007/BF01312953

M3 - Article

C2 - 6745039

AN - SCOPUS:0021153598

VL - 29

SP - 768

EP - 772

JO - Digestive Diseases and Sciences

JF - Digestive Diseases and Sciences

SN - 0163-2116

IS - 8

ER -