Intra-articular analgesia for arthroscopic meniscectomy

B. Lyons, D. Lohan, C. G. Flynn, G. P. Joshi, T. M. O'Brien, M. McCarroll

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

Intra-articular morphine has been shown to provide prolonged analgesia after arthroscopic knee surgery; the addition of local anaesthetic agents has been reported to improve this analgesic effect. Pethidine possesses local anaesthetic properties, and therefore this study was designed to evaluate its analgesic efficacy after arthroscopic meniscectomy. Sixty patients were allocated randomly to receive intra-articular injections of pethidine 50 mg, morphine 5 mg or saline after elective arthroscopic meniscectomy. Postoperative pain was assessed using an interval visual analogue scale and measuring analgesic requirements. Both treatment groups had significantly lower pain scores compared with the control group. Patients in the pethidine group had lower pain scores than those in the morphine group at 0.5, 1 and 2 h, but significantly higher scores at 12 and 24 h. These observations suggest that the local anaesthetic effect of pethidine may be responsible for the improved early analgesia, but its duration of action appears to be less than that of morphine.

Original languageEnglish (US)
Pages (from-to)552-555
Number of pages4
JournalBritish Journal of Anaesthesia
Volume75
Issue number5
DOIs
StatePublished - Jan 1 1995

Keywords

  • Analgesia, postoperative
  • Analgesic techniques,intraarticular
  • Analgesics opioid, morphine
  • Analgesics opioid, pethidine
  • Surgery, orthopaedic

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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    Lyons, B., Lohan, D., Flynn, C. G., Joshi, G. P., O'Brien, T. M., & McCarroll, M. (1995). Intra-articular analgesia for arthroscopic meniscectomy. British Journal of Anaesthesia, 75(5), 552-555. https://doi.org/10.1093/bja/75.5.552