Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation

Judith A. Whittum, Jerry Y Niederkorn, James P McCulley, J. Wayne Streilein

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

Herpes simplex virus Type 1 (HSV-1) inoculated intracamerally (IC) into the anterior chamber of BALB/c eyes induces anterior chamber associated immune deviation (ACAID) in which T cell-mediated delayed type hypersensitivity (DTK) responses to HSV-1 are impaired while B cell-mediated anti-HSV neutralizing antibody responses are intact or enhanced.

Original languageEnglish (US)
Pages (from-to)691-697
Number of pages7
JournalCurrent Eye Research
Volume2
Issue number10
DOIs
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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