Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation

Judith A. Whittum, Jerry Y Niederkorn, James P McCulley, J. Wayne Streilein

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Herpes simplex virus Type 1 (HSV-1) inoculated intracamerally (IC) into the anterior chamber of BALB/c eyes induces anterior chamber associated immune deviation (ACAID) in which T cell-mediated delayed type hypersensitivity (DTK) responses to HSV-1 are impaired while B cell-mediated anti-HSV neutralizing antibody responses are intact or enhanced.

Original languageEnglish (US)
Pages (from-to)691-697
Number of pages7
JournalCurrent Eye Research
Volume2
Issue number10
DOIs
StatePublished - 1982

Fingerprint

Human Herpesvirus 1
Anterior Chamber
Simplexvirus
Delayed Hypersensitivity
Neutralizing Antibodies
Antibody Formation
B-Lymphocytes
T-Lymphocytes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation. / Whittum, Judith A.; Niederkorn, Jerry Y; McCulley, James P; Streilein, J. Wayne.

In: Current Eye Research, Vol. 2, No. 10, 1982, p. 691-697.

Research output: Contribution to journalArticle

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