TY - JOUR
T1 - Intracranial trigeminal nerve rhabdomyoma/choristoma in a child
T2 - A case report and discussion of possible histogenesis
AU - Zwick, David L.
AU - Livingston, Kim
AU - Clapp, Larry
AU - Kosnik, Edward
AU - Yates, Allen
PY - 1989/4
Y1 - 1989/4
N2 - Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumors and their true neoplastic nature are matters of controversy. We report the first case of a rhabdomyoma located inside the cranium. The intimate association with the mandibular division of the trigeminal nerve, the normal embryogenesis of the craniofacial muscles, and animal homograft and xenograft experiments provide a framework for considering this tumor, and possibly other rhabdomyomas, as a choristoma/hamartoma rather than a true neoplasm.
AB - Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumors and their true neoplastic nature are matters of controversy. We report the first case of a rhabdomyoma located inside the cranium. The intimate association with the mandibular division of the trigeminal nerve, the normal embryogenesis of the craniofacial muscles, and animal homograft and xenograft experiments provide a framework for considering this tumor, and possibly other rhabdomyomas, as a choristoma/hamartoma rather than a true neoplasm.
KW - intracranial rhabdomyoma
KW - neuromuscular hamartoma
KW - rhabdomyoma
KW - trigeminal nerve rhabdomyoma
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U2 - 10.1016/0046-8177(89)90050-6
DO - 10.1016/0046-8177(89)90050-6
M3 - Article
C2 - 2703230
AN - SCOPUS:0024588524
SN - 0046-8177
VL - 20
SP - 390
EP - 392
JO - Human Pathology
JF - Human Pathology
IS - 4
ER -