Intraneural perineurioma of the radial nerve in a child

An intraneural perineurioma is an uncommon solitary neoplasm of major nerve trunks composed of perineurial cells from the peripheral nerve sheath. The typical course of intraneural perineurioma is indolent, with gradual-onset motor loss and presentation for evaluation months to years after onset of symptoms. We report a 9-year-old girl with an intraneural perineurioma of the radial nerve. Diagnosis was confirmed by histology and immunohistochemistry. Resection and nerve graft reconstruction were performed to prevent progression of motor compromise and to allow recovery of motor function. An algorithm for the management of focal intraneural tumors is shown.