Intraoperative MRI for high and low grade gliomas

Tomas Garzon-Muvdi, George Samandouras

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Gliomas are central nervous system neoplasms that infiltrate the surrounding brain parenchyma, complicating their treatment. Tools that increase extent of resection (EOR) while preventing neurological deficit are vital for improving outcomes for patients diagnosed with gliomas. Intraoperative MRI (iMRI) can be used in the surgical resection of gliomas and has demonstrated great potential for maximizing extent of resection for both high and low grade gliomas in an attempt to improve patient outcomes. iMRI is a promising adjunct for the neurosurgical operating theater that is safe and effective in increasing EOR. However, it has limitations such as cost and need for specialized equipment. Although the majority of evidence is encouraging, it is primarily derived from retrospective studies, thus emphasizing the need for randomized trials more evident and necessary. Here, we review the current evidence supporting the use of iMRI for the resection of gliomas, the potential advantages, and limitations of this imaging technique in the operating room.

Original languageEnglish (US)
Title of host publicationComprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors
PublisherElsevier
Pages347-356
Number of pages10
ISBN (Electronic)9780128117835
ISBN (Print)9780128117842
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Keywords

  • Extent of resection
  • High grade glioma
  • Intraoperative MRI
  • Low grade glioma

ASJC Scopus subject areas

  • Medicine(all)

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