Introduction to Theme "chromatin, epigenetics, and Transcription"

Joan W. Conaway

doi:10.1146/annurev-biochem-090711-093103

Introduction to Theme "chromatin, epigenetics, and Transcription"

Joan W. Conaway

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Transcriptional regulation in eukaryotes depends on a complex network of interactions between RNA polymerases and a host of transcription factors and coregulators that control their activity during transcription initiation and elongation. Among these are an enormous variety of enzymes and proteins that modulate chromatin structure via changes in DNA methylation, histone modifications, and nucleosome location. This volume of the Annual Review of Biochemistry contains a set of four reviews addressing the interplay between mechanisms that regulate DNA methylation, chromatin structure, and transcription.

Original language	English (US)
Pages (from-to)	61-64
Number of pages	4
Journal	Annual review of biochemistry
Volume	81
DOIs	https://doi.org/10.1146/annurev-biochem-090711-093103
State	Published - Jul 2012
Externally published	Yes

Keywords

DNA methylation
RNA polymerase II
elongation
histone modification
noncoding RNA

ASJC Scopus subject areas

Biochemistry

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10.1146/annurev-biochem-090711-093103

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AB - Transcriptional regulation in eukaryotes depends on a complex network of interactions between RNA polymerases and a host of transcription factors and coregulators that control their activity during transcription initiation and elongation. Among these are an enormous variety of enzymes and proteins that modulate chromatin structure via changes in DNA methylation, histone modifications, and nucleosome location. This volume of the Annual Review of Biochemistry contains a set of four reviews addressing the interplay between mechanisms that regulate DNA methylation, chromatin structure, and transcription.

KW - DNA methylation

KW - RNA polymerase II

KW - elongation

KW - histone modification

KW - noncoding RNA

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Introduction to Theme "chromatin, epigenetics, and Transcription"

Abstract

Keywords

ASJC Scopus subject areas

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