Introduction to Theme "chromatin, epigenetics, and Transcription"

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Transcriptional regulation in eukaryotes depends on a complex network of interactions between RNA polymerases and a host of transcription factors and coregulators that control their activity during transcription initiation and elongation. Among these are an enormous variety of enzymes and proteins that modulate chromatin structure via changes in DNA methylation, histone modifications, and nucleosome location. This volume of the Annual Review of Biochemistry contains a set of four reviews addressing the interplay between mechanisms that regulate DNA methylation, chromatin structure, and transcription.

Original languageEnglish (US)
Pages (from-to)61-64
Number of pages4
JournalAnnual review of biochemistry
Volume81
DOIs
StatePublished - Jul 2012
Externally publishedYes

Keywords

  • DNA methylation
  • elongation
  • histone modification
  • noncoding RNA
  • RNA polymerase II

ASJC Scopus subject areas

  • Biochemistry

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