Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials

Joseph M. Caster, Artish N. Patel, Tian Zhang, Andrew Wang

Research output: Contribution to journalReview articlepeer-review

225 Scopus citations

Abstract

Nanomedicine is a relatively new field that is rapidly evolving. Formulation of drugs on the nanoscale imparts many physical and biological advantages. Such advantages can in turn translate into improved therapeutic efficacy and reduced toxicity. While approximately 50 nanotherapeutics have already entered clinical practice, a greater number of drugs are undergoing clinical investigation for a variety of indications. This review aims to examine all the nanoformulations that are currently undergoing clinical investigation and their outlook for ultimate clinical translation. WIREs Nanomed Nanobiotechnol 2017, 9:e1416. doi: 10.1002/wnan.1416. For further resources related to this article, please visit the WIREs website.

Original languageEnglish (US)
Article numbere1416
JournalWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
Volume9
Issue number1
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering

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