Ionic interaction with bone mineral IV. Varying affinity of synthetic calcium phosphates for Ca2+

Charles Y C Pak, H. Catherine W Skinner

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The concentration of Ca2+ and PO43- in the liquid film surrounding the crystals of several synthetic calcium phosphates suspended in an aqueous medium was calculated from 45Ca2+ and 32PO43- exchange studies performed under physiological conditions. This permitted an estimation of the uptake of Ca2+ and PO43- from solution by the solid phase alone, exclusive of the uptake by the adherent liquid film. The compounds with low calcium-to-phosphate molar ratio (Ca/P) showed a greater affinity for Ca2+ than those with higher Ca/P. Octacalcium phosphate (Ca/P = 1.33) incorporated considerably more Ca2+ than PO43-. Tricalcium phosphate (Ca/P = 1.5), Bio-Rad apatite (Ca/P = 1.51), G-D apatite (Ca/P = 1.63), and L-apatite (Ca/P = 1.67), all of which gave apatitic X-ray diffraction patterns, demonstrated an uptake of Ca2+ in decreasing order, and an uptake of PO43- in increasing order.

Original languageEnglish (US)
Pages (from-to)274-282
Number of pages9
JournalBBA - General Subjects
Volume165
Issue number2
DOIs
StatePublished - Sep 3 1968

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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