ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements

Maria M. Crespo, Erika D. Lease, Amparo Sole, Nora Sandorfi, Laurie D. Snyder, Gerald J. Berry, Jérôme Le Pavec, Aida E. Venado, Jose M. Cifrian, Hilary Goldberg, Daniel F. Dilling, Cynthia Gries, Arun Nair, Keith Willie, Keith C. Meyer, Rupal J. Shah, Sofya Tokman, Are Holm, Caroline M. Patterson, Tanya McWilliamsOsnat Shtraichman, Brad Bemiss, Juan Salgado, Carol Farver, Heather Strah, Katharina Wassilew, Vaidehi Kaza, Molly Howsare, Michelle Murray, Sangeeta Bhorade, Marie Budev

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Patients with connective tissue disease (CTD) and advanced lung disease are often considered suboptimal candidates for lung transplantation (LTx) due to their underlying medical complexity and potential surgical risk. There is substantial variability across LTx centers regarding the evaluation and listing of these patients. The International Society for Heart and Lung Transplantation-supported consensus document on lung transplantation in patients with CTD standardization aims to clarify definitions of each disease state included under the term CTD, to describe the extrapulmonary manifestations of each disease requiring consideration before transplantation, and to outline the absolute contraindications to transplantation allowing risk stratification during the evaluation and selection of candidates for LTx.

Original languageEnglish (US)
Pages (from-to)1251-1266
Number of pages16
JournalJournal of Heart and Lung Transplantation
Volume40
Issue number11
DOIs
StatePublished - Nov 2021

Keywords

  • connective tissue diseases
  • consensus statement
  • extrapulmonary conditions
  • lung transplantation
  • transplant candidacy criteria
  • transplant evaluation

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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