Isolated relative afferent pupillary defect secondary to contralateral midbrain compression

Cheun Ju Chen, Mia Scheufele, Maushmi Sheth, Amir Torabi, Robert N Hogan, Elliot Frohman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: Relative afferent pupillary defects are typically related to ipsilateral lesions within the anterior visual pathways. Objective: To describe a patient who had a workup for headache and was found to have an isolated left relative afferent pupillary defect without any other neurological findings. Design: We review the neuroanatomy of the pupillary light reflex pathway and emphasize the nasotemporal bias of decussating fiber projections, which accounts for the relative afferent pupillary defect contralateral to the described lesion. Result: Magnetic resonance imaging of the brain revealed a pineal tumor compressing the right rostral midbrain. Conclusion: While rare, a relative afferent pupillary defect can occasionally occur secondary to lesions in the postchiasmal pathways. In these circumstances, the pupillary defect will be observed to be contralateral to the side of the lesion.

Original languageEnglish (US)
Pages (from-to)1451-1453
Number of pages3
JournalArchives of Neurology
Volume61
Issue number9
DOIs
StatePublished - Sep 2004

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Pupil Disorders
Mesencephalon
Pupillary Reflex
Pinealoma
Neuroanatomy
Visual Pathways
Headache
Magnetic Resonance Imaging
Light
Defects
Compression
Brain
Lesion
Pathway

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Isolated relative afferent pupillary defect secondary to contralateral midbrain compression. / Chen, Cheun Ju; Scheufele, Mia; Sheth, Maushmi; Torabi, Amir; Hogan, Robert N; Frohman, Elliot.

In: Archives of Neurology, Vol. 61, No. 9, 09.2004, p. 1451-1453.

Research output: Contribution to journalArticle

Chen, Cheun Ju ; Scheufele, Mia ; Sheth, Maushmi ; Torabi, Amir ; Hogan, Robert N ; Frohman, Elliot. / Isolated relative afferent pupillary defect secondary to contralateral midbrain compression. In: Archives of Neurology. 2004 ; Vol. 61, No. 9. pp. 1451-1453.
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