Isolation and analysis of discreet human prostate cellular populations

Douglas W. Strand, LaTayia Aaron, Gervaise Henry, Omar E. Franco, Simon W. Hayward

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The use of lineage tracing in transgenic mouse models has revealed an abundance of subcellular phenotypes responsible for maintaining prostate homeostasis. The ability to use fresh human tissues to examine the hypotheses generated by these mouse experiments has been greatly enhanced by technical advances in tissue processing, flow cytometry and cell culture. We describe in detail the optimization of protocols for each of these areas to facilitate research on solving human prostate diseases through the analysis of human tissue.

Original languageEnglish (US)
JournalDifferentiation
DOIs
StateAccepted/In press - Oct 23 2015

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ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology
  • Molecular Biology
  • Cancer Research

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