TY - JOUR
T1 - Isozymes of fructose 6-phosphate,2-kinase
T2 - Fructose-2,6-bisphosphatase in rat and bovine heart, liver, and skeletal muscle
AU - Taniyama, Matsuo
AU - Kitamura, Kazuo
AU - Thomas, Helmut
AU - Lawson, J. W R
AU - Uyeda, Kosaku
PY - 1988/12/30
Y1 - 1988/12/30
N2 - The distribution of Fructose 6-P,2-kinase:Fructose 2,6-bisphosphatase in rat and bovine heart, liver, and skeletal muscle tissues was examined. With DEAE-cellulose chromatography, two peaks (I and II) of Fru 6-P,2-kinase activity were detected in all tissue extracts. Peak I was the predominant form both in rat and bovine heart tissue, while peak II was the major form in liver and skeletal muscle. Antibodies to heart enzyme reacted specifically with peak I, and antibodies to liver enzyme reacted with peak II from both liver and skeletal muscle. All the isozymes were bifunctional. All the tissues examined contained other isozymes in minor amounts.
AB - The distribution of Fructose 6-P,2-kinase:Fructose 2,6-bisphosphatase in rat and bovine heart, liver, and skeletal muscle tissues was examined. With DEAE-cellulose chromatography, two peaks (I and II) of Fru 6-P,2-kinase activity were detected in all tissue extracts. Peak I was the predominant form both in rat and bovine heart tissue, while peak II was the major form in liver and skeletal muscle. Antibodies to heart enzyme reacted specifically with peak I, and antibodies to liver enzyme reacted with peak II from both liver and skeletal muscle. All the isozymes were bifunctional. All the tissues examined contained other isozymes in minor amounts.
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U2 - 10.1016/S0006-291X(88)80966-5
DO - 10.1016/S0006-291X(88)80966-5
M3 - Article
C2 - 2849948
AN - SCOPUS:0024202710
SN - 0006-291X
VL - 157
SP - 949
EP - 954
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 3
ER -