Issues of prematurity and HIV infection

Julie Mirpuri, Lucky Jain

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Prematurity and HIV present a complex challenge, with biologic underpinnings that are often confounded by a myriad of other factors that coexist in this high-risk population. Furthermore, many of the current management options designed to reduce mother-to-infant transmission, including antiretroviral therapy and cesarean birth, may each have an independent effect on prematurity. These issues notwithstanding, knowledge gained from randomized controlled trials and epidemiologic studies has made a significant impact on the approach to this challenging public health problem worldwide. This article discusses the significance, contribution, and management of perinatal transmission of HIV in prematurity.

Original languageEnglish (US)
Pages (from-to)887-905
Number of pages19
JournalClinics in Perinatology
Volume37
Issue number4
DOIs
StatePublished - Dec 1 2010

Keywords

  • Antiretroviral therapy
  • Cesarean delivery
  • HIV
  • Late preterm
  • Perinatal transmission
  • Premature infant
  • Preterm birth

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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