Juvenile polyps and juvenile polyp syndromes in children: A clinical and endoscopic survey

Brandy Hood, Steven Bigler, Phyllis Bishop, Hua Liu, Naveed Ahmad, MacEy Renault, Michael Nowicki

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

In children, most colonic polyps are juvenile polyps with negligible risk for malignant transformation. The exception is juvenile polyposis syndrome (JPS) where there is a risk for developing colon cancer. The authors studied differences in clinical features and colonoscopic findings in children with solitary juvenile polyps (SJP), multiple juvenile polyps (MJP), and JPS. Methods. Children were identified as SJP (1 polyp), MJP (2-4 polyps), or JPS (>5 polyps). Demographic data, laboratory values, family history, and colonoscopic findings were recorded. Results. Children having polypectomy had juvenile polyps (93%), adenomatous polyps (5%), and Peutz-Jegher syndrome (3%). Juvenile polyps were classified as SJP (67%), MJP (16%), and JPS (17%). Children with SJP were younger, were more likely to have polyps limited to the rectosigmoid colon, and had larger polyps than children with MJP and JPS. Anemia was more common in JPS than MJP and SJP. Conclusion. Clinical and endoscopic findings differ between SJP, MJP, and JPS.

Original languageEnglish (US)
Pages (from-to)910-915
Number of pages6
JournalClinical Pediatrics
Volume50
Issue number10
DOIs
StatePublished - Oct 1 2011

Keywords

  • immunohistochemical markers
  • juvenile polyposis syndrome
  • juvenile polyps
  • malignant potential

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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