Keratinization of the bulbar conjunctival epithelium in superior limbic keratoconjunctivitis in humans. An electron microscopic study

H. B. Collin, P. C. Donshik, C. S. Foster, S. A. Boruchoff, Harrison D Cavanagh

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A prominent histological feature of superior limbic keratoconjunctivitis is the presence of keratinization of the superior bulbar conjunctiva. Ultrastructurally the affected conjunctival epithelium shows all of the characteristics of keratinization as described in skin. There is a superficial layer of horny cells with reduced organelles and thickened cell membrane. In the intermediate layers, the cells contain an increased number of cytoplasmic filaments which are sometimes aggregated into dense masses, keratohyalin granules, both in the cytoplasm and in the nucleus, membrane coating granules, lysosomes and various other types of membranous structures.

Original languageEnglish (US)
Pages (from-to)531-543
Number of pages13
JournalActa Ophthalmologica
Volume56
Issue number4
StatePublished - 1978

Fingerprint

Keratoconjunctivitis
Epithelium
Electrons
Conjunctiva
Lysosomes
Cytoskeleton
Organelles
Cytoplasm
Cell Membrane
Skin
Membranes
keratohyalin

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Keratinization of the bulbar conjunctival epithelium in superior limbic keratoconjunctivitis in humans. An electron microscopic study. / Collin, H. B.; Donshik, P. C.; Foster, C. S.; Boruchoff, S. A.; Cavanagh, Harrison D.

In: Acta Ophthalmologica, Vol. 56, No. 4, 1978, p. 531-543.

Research output: Contribution to journalArticle

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