KERATINIZATION OF THE BULBAR CONJUNCTIVAL EPITHELIUM IN SUPERIOR LIMBIC KERATOCONJUNCTIVITIS IN HUMANS: An Electron Microscopic Study

H. B. Collin, P. C. Donshik, C. S. Foster, S. A. Boruchoff, Harrison D Cavanagh

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

A prominent histological feature of superior limbic keratoconjunctivitis is the presence of keratinization of the superior bulbar conjunctiva. Ultra‐structurally the affected conjunctival epithelium shows all of the characteristics of keratinization as described in skin. There is a superficial layer of horny cells with reduced organelles and thickened cell membrane. In the intermediate layers, the cells contain an increased number of cytoplasmic filaments which are sometimes aggregated into dense masses, kera‐tohyalin granules, both in the cytoplasm and in the nucleus, membrane coating granules, lysosomes and various other types of membranous structures. 1978 Institution Acta Ophthalmologica Scandinavica

Original languageEnglish (US)
Pages (from-to)531-543
Number of pages13
JournalActa Ophthalmologica
Volume56
Issue number4
DOIs
StatePublished - Aug 1978

Keywords

  • conjunctivitis
  • electron microscopy
  • keratinization
  • keratohyalin
  • superior limbic keratoconjunctivitis

ASJC Scopus subject areas

  • Ophthalmology

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