Abstract
The dysregulation of specific cellular functions in adipocytes, muscle cells, β cells, and the liver leads to changes in systemic metabolic processes and ultimately to the pathophysiological manifestations that cause type 2 diabetes. The underlying cellular mechanisms are complex. The two meetings summarized here aimed to highlight the recent advances in our understanding of the molecular basis of feeding and nutrient storage and on the molecular consequences of obesity in terms of promoting risk for type 2 diabetes and cardiovascular disease.
Original language | English (US) |
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Pages (from-to) | 2193-2201 |
Number of pages | 9 |
Journal | Genes and Development |
Volume | 20 |
Issue number | 16 |
DOIs | |
State | Published - Aug 15 2006 |
Keywords
- Adipocyte
- Diabetes
- ER stress
- Inflammation
- Mitochondria
ASJC Scopus subject areas
- Genetics
- Developmental Biology