KLF4 Initiates Acinar Cell Reprogramming and Is Essential for the Early Stages of Pancreatic Carcinogenesis

Ravikanth Maddipati, Jonathan P. Katz

Research output: Contribution to journalShort survey

6 Scopus citations

Abstract

Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and is minimally responsive to current chemotherapies. In this issue of Cancer Cell, Xie et al. (2016) identify the transcription factor KLF4 as essential for the early stages of pancreatic carcinogenesis, expanding the repertoire of targets for early intervention strategies.

Original languageEnglish (US)
Pages (from-to)247-248
Number of pages2
JournalCancer Cell
Volume29
Issue number3
DOIs
StatePublished - Mar 14 2016
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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