Klotho, an aging-suppressor gene

Kevin P. Rosenblatt, Makoto Kuro-o

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Suppression of aging and its effects is a far-reaching dream of human beings. To turn this dream into a scientific reality, it is essential to understand the molecular mechanisms that underlie the aging process. A coherent understanding of these mechanisms is expected to allow us to develop rational strategies for slowing the aging process, which is the most significant risk factor for many age-related disorders including diabetes, heart attack, stroke, osteoporosis, cancer, and dementia. Therefore, any remedy against the progression of aging may reduce and/or delay premature death and disability caused by multiple age-related diseases simultaneously. This could lead to a tremendous increase in both the length and quality of human life.

Original languageEnglish (US)
Pages (from-to)191-203
Number of pages13
JournalHormone Research
Volume67
Issue numberSUPPL. 1
DOIs
StatePublished - Feb 2007

Fingerprint

Suppressor Genes
Premature Mortality
Osteoporosis
Dementia
Stroke
Myocardial Infarction
Quality of Life
Neoplasms

Keywords

  • FGF signaling
  • Insulin signaling oxidative stress
  • Klotho, aging

ASJC Scopus subject areas

  • Endocrinology

Cite this

Klotho, an aging-suppressor gene. / Rosenblatt, Kevin P.; Kuro-o, Makoto.

In: Hormone Research, Vol. 67, No. SUPPL. 1, 02.2007, p. 191-203.

Research output: Contribution to journalArticle

Rosenblatt, KP & Kuro-o, M 2007, 'Klotho, an aging-suppressor gene', Hormone Research, vol. 67, no. SUPPL. 1, pp. 191-203. https://doi.org/10.1159/000097581
Rosenblatt, Kevin P. ; Kuro-o, Makoto. / Klotho, an aging-suppressor gene. In: Hormone Research. 2007 ; Vol. 67, No. SUPPL. 1. pp. 191-203.
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