Klotho-induced insulin resistance: A blessing in disguise?

Roger H Unger

Research output: Contribution to journalShort surveypeer-review

53 Scopus citations

Abstract

Insulin resistance can be good for your health when it is caused by klotho, a hormone that prolongs life. A reduction in insulin-stimulated intracellular glucose availability may prevent intracellular lipid overload and lipotoxicity, a proposed mechanism of hte life-shortening metabolic syndrome.

Original languageEnglish (US)
Pages (from-to)56-57
Number of pages2
JournalNature medicine
Volume12
Issue number1
DOIs
StatePublished - Jan 2006

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

Fingerprint

Dive into the research topics of 'Klotho-induced insulin resistance: A blessing in disguise?'. Together they form a unique fingerprint.

Cite this