Klotho-induced insulin resistance: A blessing in disguise?

Roger H Unger

Research output: Contribution to journalShort surveypeer-review

46 Scopus citations


Insulin resistance can be good for your health when it is caused by klotho, a hormone that prolongs life. A reduction in insulin-stimulated intracellular glucose availability may prevent intracellular lipid overload and lipotoxicity, a proposed mechanism of hte life-shortening metabolic syndrome.

Original languageEnglish (US)
Pages (from-to)56-57
Number of pages2
JournalNature medicine
Issue number1
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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