Laparoscopic and open retroperitoneal lymph-node dissection for clinical stage I nonseminomatous germ-cell testis tumors

Khaled F. Abdel-Aziz, J. Kyle Anderson, Robert Svatek, Vitaly Margulis, Arthur I Sagalowsky, Jeffrey A Cadeddu

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Abstract

Background and Purpose: Laparoscopic retroperitoneal lymph node dissection (L-RPLND) has been reported as efficacious for staging of the retroperitoneum in patients with stage I nonseminomatous germ-cell testis tumors (NSGCT). However, reports are limited to a few centers, and this procedure has yet to be widely accepted as an alternative to open retroperitoneal lymph node dissection (O-RPLND). Thus, we compared our contemporary open and laparoscopic experience with RPLND. Patients and Methods: A retrospective chart review identified 28 patients who underwent either open (N = 6) or laparoscopic (N = 22) RPLND for clinical stage I NSGCT since 2000. Each patient received the appropriate modified template dissection. Perioperative demographic data, histologic nodal status, and recurrence data were evaluated. The mean follow-up was similar in the two groups. Results: The mean operative time was not significantly different (313 minutes for L-RPLND v 284 minutes for O-RPLND). However, L-RPLND did have a significantly shorter hospitalization (1.2 v 8.5 days). Significantly more lymph nodes were removed with O-LPLND than with L-RPLND (mean 33 v 17). There was a single recurrence outside the modified template after both L-RPLND and O-RPLND and one within-the-template recurrence in the O-RPLND group. Conclusions: The L-RPLND is associated with less blood loss and a shorter hospital stay than O-RPLND, whereas the lymph-node yield of O-RPLND is greater. However, during the critical early follow-up period, the oncologic effectiveness and morbidity of L-RPLND for clinical stage I NSGCT appears similar to that of O-RPLND.

Original languageEnglish (US)
Pages (from-to)627-631
Number of pages5
JournalJournal of Endourology
Volume20
Issue number9
DOIs
StatePublished - Sep 2006

Fingerprint

Lymph Node Excision
Testis
Nonseminomatous germ cell tumor
Recurrence
Lymph Nodes
Operative Time
Dissection
Length of Stay
Hospitalization
Demography

ASJC Scopus subject areas

  • Urology

Cite this

Laparoscopic and open retroperitoneal lymph-node dissection for clinical stage I nonseminomatous germ-cell testis tumors. / Abdel-Aziz, Khaled F.; Anderson, J. Kyle; Svatek, Robert; Margulis, Vitaly; Sagalowsky, Arthur I; Cadeddu, Jeffrey A.

In: Journal of Endourology, Vol. 20, No. 9, 09.2006, p. 627-631.

Research output: Contribution to journalArticle

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