Laparoscopic partial nephrectomy with a diode laser

Porcine results

Kenneth Ogan, David Wilhelm, Guy Lindberg, Yair Lotan, Cheryl Napper, John Hoopman, Margaret S Pearle, Jeffrey A Cadeddu

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Purpose: To develop a safe and effective technique for laparoscopic partial nephrectomy without need for hilar occlusion. Materials and Methods: Laparoscopic transperitoneal lower-pole partial nephrectomy was performed in five 45- to 50-kg female farm pigs using a 980-nm diode laser. Standard transperitoneal access was obtained, and a four-port approach was used to perform a laparoscopic right partial nephrectomy using a diode laser (23 W) without hilar occlusion. The pigs were allowed to recover and 2 weeks later underwent a left laparoscopic partial nephrectomy. Postoperatively, renal function was monitored by serial serum creatinine measurements. Both kidneys and ureters were removed for ex-vivo retrograde pyelograms and histologic analysis. Results: The 980-nm diode laser resulted in successful lower-pole partial nephrectomy without hilar occlusion in all 10 of the kidneys. In three cases, laser hemostasis was insufficient, and adjunctive hemostatic clips were necessary to stop bleeding. The mean operative time was 126 minutes, and the mean laser time was 84 minutes. An average of 23% (range 13%-33%) of the kidney parenchyma was resected. The mean blood loss was 150 mL (range 50-300 mL). There was no evidence of urinary extravasation on ex-vivo retrograde pyelograms at 2 weeks in any of the kidneys. Conclusion: Laparoscopic partial nephrectomy without hilar occlusion using the 980-nm diode laser is feasible in the porcine model. Because adjunctive hemostatic measures may be necessary in some cases, clinical trials in humans should be limited to small exophytic tumors.

Original languageEnglish (US)
Pages (from-to)749-753
Number of pages5
JournalJournal of Endourology
Volume16
Issue number10
StatePublished - Dec 2002

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Semiconductor Lasers
Nephrectomy
Swine
Kidney
Urography
Hemostatics
Lasers
Ureter
Operative Time
Hemostasis
Surgical Instruments
Creatinine
Clinical Trials
Hemorrhage
Serum
Neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Ogan, K., Wilhelm, D., Lindberg, G., Lotan, Y., Napper, C., Hoopman, J., ... Cadeddu, J. A. (2002). Laparoscopic partial nephrectomy with a diode laser: Porcine results. Journal of Endourology, 16(10), 749-753.

Laparoscopic partial nephrectomy with a diode laser : Porcine results. / Ogan, Kenneth; Wilhelm, David; Lindberg, Guy; Lotan, Yair; Napper, Cheryl; Hoopman, John; Pearle, Margaret S; Cadeddu, Jeffrey A.

In: Journal of Endourology, Vol. 16, No. 10, 12.2002, p. 749-753.

Research output: Contribution to journalArticle

Ogan, K, Wilhelm, D, Lindberg, G, Lotan, Y, Napper, C, Hoopman, J, Pearle, MS & Cadeddu, JA 2002, 'Laparoscopic partial nephrectomy with a diode laser: Porcine results', Journal of Endourology, vol. 16, no. 10, pp. 749-753.
Ogan K, Wilhelm D, Lindberg G, Lotan Y, Napper C, Hoopman J et al. Laparoscopic partial nephrectomy with a diode laser: Porcine results. Journal of Endourology. 2002 Dec;16(10):749-753.
Ogan, Kenneth ; Wilhelm, David ; Lindberg, Guy ; Lotan, Yair ; Napper, Cheryl ; Hoopman, John ; Pearle, Margaret S ; Cadeddu, Jeffrey A. / Laparoscopic partial nephrectomy with a diode laser : Porcine results. In: Journal of Endourology. 2002 ; Vol. 16, No. 10. pp. 749-753.
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