Large malignant phyllodes tumor of the breast with metastases to the lungs

Alexander Augustyn, Sunati Sahoo, Rachel D. Wooldridge

Research output: Contribution to journalArticle

Abstract

Phyllodes tumors of the breast account for less than 0.5% of breast cancers and present most commonly in women 45 to 49 years old. The importance in managing fibroepithelial lesions lies in distinguishing fibroadenomas, which are benign, from phyllodes tumors, which can be malignant and require complete surgical excision. We report the case of a 56-year-old female who presented with a rapidly enlarging mass in her right breast 18 cm in maximum dimension that completely effaced the breast and distorted the nipple. The patient underwent a successful total mastectomy after core biopsy revealed a diagnosis of phyllodes tumor. Surgical resection is the primary treatment modality; neoadjuvant and adjuvant therapies remain controversial. Here, we report the case of a large malignant phyllodes tumor metastatic to the lungs, review the literature, and discuss diagnostic modalities and adjunct nonsurgical therapies.

Original languageEnglish (US)
Article number5684
Pages (from-to)69-72
Number of pages4
JournalRare Tumors
Volume7
Issue number2
StatePublished - 2015

Fingerprint

Phyllodes Tumor
Breast Neoplasms
Neoplasm Metastasis
Lung
Breast
Simple Mastectomy
Fibroadenoma
Neoadjuvant Therapy
Nipples
Biopsy
Therapeutics

Keywords

  • Breast
  • Metastatic
  • Phyllodes tumor
  • Surgery

ASJC Scopus subject areas

  • Oncology
  • Histology

Cite this

Augustyn, A., Sahoo, S., & Wooldridge, R. D. (2015). Large malignant phyllodes tumor of the breast with metastases to the lungs. Rare Tumors, 7(2), 69-72. [5684].

Large malignant phyllodes tumor of the breast with metastases to the lungs. / Augustyn, Alexander; Sahoo, Sunati; Wooldridge, Rachel D.

In: Rare Tumors, Vol. 7, No. 2, 5684, 2015, p. 69-72.

Research output: Contribution to journalArticle

Augustyn, A, Sahoo, S & Wooldridge, RD 2015, 'Large malignant phyllodes tumor of the breast with metastases to the lungs', Rare Tumors, vol. 7, no. 2, 5684, pp. 69-72.
Augustyn, Alexander ; Sahoo, Sunati ; Wooldridge, Rachel D. / Large malignant phyllodes tumor of the breast with metastases to the lungs. In: Rare Tumors. 2015 ; Vol. 7, No. 2. pp. 69-72.
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