Large-scale chronically implantable precision motorized microdrive array for freely behaving animals

Jun Yamamoto, Matthew A. Wilson

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Multiple single-unit recording has become one of the most powerful in vivo electro-physiological techniques for studying neural circuits. The demand has been increasing for small and lightweight chronic recording devices that allow fine adjustments to be made over large numbers of electrodes across multiple brain regions. To achieve this, we developed precision motorized microdrive arrays that use a novel motor multiplexing headstage to dramatically reduce wiring while preserving precision of the microdrive control. Versions of the microdrive array were chronically implanted on both rats (21 microdrives) and mice (7 microdrives), and relatively long-term recordings were taken.

Original languageEnglish (US)
Pages (from-to)2430-2440
Number of pages11
JournalJournal of neurophysiology
Volume100
Issue number4
DOIs
StatePublished - Oct 2008

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology

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