Late MRI after head injury in children: relationship to clinical features and outcome

Dianne Mendelsohn, Harvey S. Levin, Derek Bruce, Matthew Lilly, Harriet Harward, Kathleen A. Culhane, Howard M. Eisenberg

Research output: Contribution to journalArticle

76 Scopus citations

Abstract

To characterize the brain pathology in relation to long-term outcome after pediatric head injury, 55 children were studied by magnetic resonance imaging (MRI) at least 3 months after sustaining moderate to severe closed head injury (CHI). Thirty-nine of the patients had abnormal signal intensity consistent with residual brain lesions, including 28 children with lesions involving the frontal lobes. The clinical features of children with frontal lesions, extrafrontal lesions, and diffuse injury were compared. The analysis disclosed that children with frontal lobe lesions were more frequently disabled than children who sustained diffuse injury. Our MRI findings indicate that residual brain lesions are more common after moderate to severe CHI in children than previously thought and that the frontal lobes are most frequently involved. Further investigation is indicated to elucidate whether distinctive cognitive and behavioral sequelae are associated with frontal lobe lesions in children.

Original languageEnglish (US)
Pages (from-to)445-452
Number of pages8
JournalChild's Nervous System
Volume8
Issue number8
DOIs
StatePublished - Dec 1 1992

Keywords

  • Children
  • Frontal lobes
  • Head injury
  • Magnetic resonance imaging
  • Outcome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Late MRI after head injury in children: relationship to clinical features and outcome'. Together they form a unique fingerprint.

  • Cite this

    Mendelsohn, D., Levin, H. S., Bruce, D., Lilly, M., Harward, H., Culhane, K. A., & Eisenberg, H. M. (1992). Late MRI after head injury in children: relationship to clinical features and outcome. Child's Nervous System, 8(8), 445-452. https://doi.org/10.1007/BF00274405