Late-stage nodular erythema elevatum diutinum

Whitney A. High, Mai P. Hoang, Kristin Stevens, Clay J. Cockerell

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Erythema elevatum diutinum (EED) is a rare chronic vasculitic process of unknown etiology that presents as bilateral, symmetrical, periarticular, red-brown papules and plaques, often over dorsa of joints. Early histologic changes are characterized by leukocytoclastic vasculitis. With chronicity, the lesions develop dense neutrophilic infiltrate and fibrosis. We describe an unusual case of late-stage nodular EED present for 35 years in a seronegative 75-year-old man. Asymptomatic papules and plaques measuring from 0.7 to 9.0 cm were seen over the interphalangeal joints, elbows, knees, and ankles. The histologic findings were characterized by predominant concentric fibrosis that formed well-circumscribed dermal and subcutaneous nodules. Awareness of this unusual presentation of EED helps to avoid misdiagnosis as cutaneous neoplasms.

Original languageEnglish (US)
Pages (from-to)764-767
Number of pages4
JournalJournal of the American Academy of Dermatology
Volume49
Issue number4
DOIs
StatePublished - Oct 1 2003

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Fibrosis
Elbow Joint
Ankle Joint
Skin Neoplasms
Knee Joint
Diagnostic Errors
Joints
Skin
Erythema elevatum diutinum

ASJC Scopus subject areas

  • Dermatology

Cite this

Late-stage nodular erythema elevatum diutinum. / High, Whitney A.; Hoang, Mai P.; Stevens, Kristin; Cockerell, Clay J.

In: Journal of the American Academy of Dermatology, Vol. 49, No. 4, 01.10.2003, p. 764-767.

Research output: Contribution to journalArticle

High, Whitney A. ; Hoang, Mai P. ; Stevens, Kristin ; Cockerell, Clay J. / Late-stage nodular erythema elevatum diutinum. In: Journal of the American Academy of Dermatology. 2003 ; Vol. 49, No. 4. pp. 764-767.
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