Abstract
Lateralization on neuroimaging was compared in cases of frontotemporal lobar degeneration (FTLD; n = 10) and cases of definite Alzheimer's disease (AD; n = 17). All of the cases were pathologically confirmed and semi-quantitative and statistical parametric mapping methods were employed. Seven of the 10 FTLD cases had lateralization on at least one neuroimaging modality: single photon emission computerized tomography (SPECT), MRI, or CT. All 6/6 FTLD cases with SPECT showed lateralization. MRI results generally agreed with SPECT findings. Three of 4 FTLD cases had lateralized atrophy on CT. For the AD cases, 10/17 SPECTs, 2/7 MRIs, and 1/9 CTs showed lateralized findings. Of the neuroimaging modalities utilized, SPECT was the most sensitive in detecting lateralization.
Original language | English (US) |
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Pages (from-to) | 324-327 |
Number of pages | 4 |
Journal | Dementia and Geriatric Cognitive Disorders |
Volume | 17 |
Issue number | 4 |
DOIs | |
State | Published - 2004 |
Keywords
- Dementia
- Frontotemporal dementia
- Frontotemporal lobar degeneration
- Single photon emission computerized tomography
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Cognitive Neuroscience
- Psychiatry and Mental health