Elevated plasma LDL cholesterol concentrations result primarily from two mechanisms: LDL overproduction and loss of hepatic receptor-dependent LDL removal. This knowledge can be used to lower plasma cholesterol and thereby retard or even reverse atherosclerosis. Pharmacologic agents are useful, as are dietary approaches.
|Original language||English (US)|
|Number of pages||12|
|Publication status||Published - 1990|
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