Lead optimization of 3-carboxyl-4(1 H)-quinolones to deliver orally bioavailable antimalarials

Yiqun Zhang, Julie A. Clark, Michele C. Connelly, Fangyi Zhu, Jaeki Min, W. Armand Guiguemde, Anupam Pradhan, Lalitha Iyer, Anna Furimsky, Jason Gow, Toufan Parman, Farah El Mazouni, Margaret A. Phillips, Dennis E. Kyle, Jon Mirsalis, R. Kiplin Guy

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