Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/-lipodystrophic mice independent of hepatocyte leptin receptors

Medicine & Life Sciences

• Leptin Receptors 75%
• Leptin 58%
• Hepatocytes 49%
• Insulin Resistance 47%
• Liver 30%
• Congenital Generalized Lipodystrophy 21%
• Response Elements 14%
• 1-Acylglycerol-3-Phosphate O-Acyltransferase 12%
• Carbohydrates 11%
• Carrier Proteins 11%
• Appetite Regulation 8%
• Hypertriglyceridemia 7%
• Fatty Liver 6%
• Corticosterone 6%
• Thyroxine 6%
• Fatty Acids 5%
• Diabetes Mellitus 5%
• Transcription Factors 4%
• Central Nervous System 4%
• Homeostasis 4%
• Insulin 4%
• Glucose 4%
• Gene Expression 3%
• Messenger RNA 3%
• Mutation 3%
• Enzymes 3%
• Therapeutics 1%

Chemical Compounds

• Leptin 100%
• Insulin Derivative 59%
• Resistance 36%
• Metabolic 12%
• Plasma 9%
• Lipogenic 9%
• Carbohydrate 8%
• Corticosterone 7%
• Mutation 4%
• Protein 4%
• Fatty Acid 4%
• Glucose 3%
• Food 3%
• Energy 2%
• Oxidation Reaction 2%