Lessons from human genetic variants in the study of B-cell differentiation

Anne B. Satterthwaite; Owen N. Witte

doi:10.1016/S0952-7915(96)80029-X

Lessons from human genetic variants in the study of B-cell differentiation

Anne B. Satterthwaite, Owen N. Witte

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Several human B-cell immunodeficiencies result from mutations in signal transducing molecules. The past year has seen significant advances in our understanding of how these molecules are integrated into B cell signaling pathways. The phenotypes of mice deficient in several of these genes have revealed species-specific differences in the requirements for early B cell development.

Original language	English (US)
Pages (from-to)	454-458
Number of pages	5
Journal	Current Opinion in Immunology
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/S0952-7915(96)80029-X
State	Published - Aug 1996

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/S0952-7915(96)80029-X

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title = "Lessons from human genetic variants in the study of B-cell differentiation",

abstract = "Several human B-cell immunodeficiencies result from mutations in signal transducing molecules. The past year has seen significant advances in our understanding of how these molecules are integrated into B cell signaling pathways. The phenotypes of mice deficient in several of these genes have revealed species-specific differences in the requirements for early B cell development.",

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year = "1996",

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AB - Several human B-cell immunodeficiencies result from mutations in signal transducing molecules. The past year has seen significant advances in our understanding of how these molecules are integrated into B cell signaling pathways. The phenotypes of mice deficient in several of these genes have revealed species-specific differences in the requirements for early B cell development.

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Lessons from human genetic variants in the study of B-cell differentiation

Abstract

ASJC Scopus subject areas

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