Leukocyte Counts in Children With Sickle Cell Disease: Comparative Values in the Steady State, Vaso-occlusive Crisis, and Bacterial Infection

G. R. Buchanan, B. E. Glader

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Total and differential WBC counts were measured in 88 children with siokle cell hemoglobinopathies during the steady state, vaso-occlusive crisis, and bacterial infection. Steady state leukocyte values were lower than anticipated on the basis of currently available information. Total and segmented leukocyte numbers were greatly increased during vaso-occlusive crisis and infection, but only with bacterial infection was there a consistent increase in bands or nonsegmented leukocytes (mean, 4,580/μl). On the basis of these data we believe that total and differential leukocyte counts are of value for identifying those children with potentially serious bacterial infections.

Original languageEnglish (US)
Pages (from-to)396-398
Number of pages3
JournalAmerican Journal of Diseases of Children
Volume132
Issue number4
DOIs
StatePublished - Apr 1978

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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