Light-induced metal-free transformations of unactivated pyridotriazoles

Ziyan Zhang, Dongari Yadagiri, Vladimir Gevorgyan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A highly efficient and practical method for incorporation of the arylmethylpyridyl moiety into diverse molecules has been developed. This method features the transition metal-free light-induced room temperature transformation of pyridotriazoles into pyridyl carbenes, which are capable of smooth arylation, X-H insertion, and cyclopropanation reactions. The synthetic usefulness of the developed method was illustrated in a facile synthesis of biologically active molecules.

Original languageEnglish (US)
Pages (from-to)8399-8404
Number of pages6
JournalChemical Science
Volume10
Issue number36
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

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Metals
Molecules
Transition metals
Temperature
carbene

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Light-induced metal-free transformations of unactivated pyridotriazoles. / Zhang, Ziyan; Yadagiri, Dongari; Gevorgyan, Vladimir.

In: Chemical Science, Vol. 10, No. 36, 01.01.2019, p. 8399-8404.

Research output: Contribution to journalArticle

Zhang, Ziyan ; Yadagiri, Dongari ; Gevorgyan, Vladimir. / Light-induced metal-free transformations of unactivated pyridotriazoles. In: Chemical Science. 2019 ; Vol. 10, No. 36. pp. 8399-8404.
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