Light-triggered chemical amplification to accelerate degradation and release from polymeric particles

Jason Olejniczak, Viet Anh Nguyen Huu, Jacques Lux, Madeleine Grossman, Sha He, Adah Almutairi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We describe a means of chemical amplification to accelerate triggered degradation of a polymer and particles composed thereof. We designed a light-degradable copolymer containing carboxylic acids masked by photolabile groups and ketals. Photolysis allows the unmasked acidic groups in the polymer backbone to accelerate ketal hydrolysis even at neutral pH.

Original languageEnglish (US)
Pages (from-to)16980-16983
Number of pages4
JournalChemical Communications
Volume51
Issue number95
DOIs
StatePublished - Sep 28 2015

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Amplification
Polymers
Degradation
Photolysis
Carboxylic Acids
Carboxylic acids
Hydrolysis
Copolymers

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Light-triggered chemical amplification to accelerate degradation and release from polymeric particles. / Olejniczak, Jason; Nguyen Huu, Viet Anh; Lux, Jacques; Grossman, Madeleine; He, Sha; Almutairi, Adah.

In: Chemical Communications, Vol. 51, No. 95, 28.09.2015, p. 16980-16983.

Research output: Contribution to journalArticle

Olejniczak, J, Nguyen Huu, VA, Lux, J, Grossman, M, He, S & Almutairi, A 2015, 'Light-triggered chemical amplification to accelerate degradation and release from polymeric particles', Chemical Communications, vol. 51, no. 95, pp. 16980-16983. https://doi.org/10.1039/c5cc06143a
Olejniczak, Jason ; Nguyen Huu, Viet Anh ; Lux, Jacques ; Grossman, Madeleine ; He, Sha ; Almutairi, Adah. / Light-triggered chemical amplification to accelerate degradation and release from polymeric particles. In: Chemical Communications. 2015 ; Vol. 51, No. 95. pp. 16980-16983.
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