Lipoprotein(a): Intrigues and insights

Helen H. Hobbs, Ann L. White

Research output: Contribution to journalReview articlepeer-review

166 Scopus citations

Abstract

Lipoprotein(a) is an atherogenic, cholesterol ester-rich lipoprotein of unknown physiological function. The unusual species distribution of lipoprotein(a) and the extreme polymorphic nature of its distinguishing apolipoprotein component, apolipoprotein(a), have provided unique challenges for the investigation of its biochemistry, genetics, metabolism and atherogenicity. Some fundamental questions regarding this enigmatic lipoprotein have escaped elucidation, as will be highlighted in this review.

Original languageEnglish (US)
Pages (from-to)225-236
Number of pages12
JournalCurrent opinion in lipidology
Volume10
Issue number3
DOIs
StatePublished - 1999

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Genetics
  • Nutrition and Dietetics
  • Cardiology and Cardiovascular Medicine
  • Cell Biology

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