Liquid chromatographic determination of less polar ginsenosides in processed ginseng

Sung Won Kwon, Sang Beom Han, Il Ho Park, Jong Moon Kim, Man Ki Park, Jeong Hill Park

Research output: Contribution to journalArticlepeer-review

221 Scopus citations

Abstract

Reversed-phase LC with an evaporative light scattering detector (ELSD) is used for the determination of less polar ginsenosides in processed ginseng. These ginsenosides include ginsenosides F4, Rg3, Rg5, Rg6, Rk1, Rk3, Rs3, Rs4, and Rs5. The method used a C18-bonded silica column with a CH3CN/H2O/CH3COOH gradient elution. (20R) and (20S) epimers and geometric isomers at the C-20 position of ginsenosides, which are not generally separated by amino columns, were now clearly separated.

Original languageEnglish (US)
Pages (from-to)335-339
Number of pages5
JournalJournal of Chromatography A
Volume921
Issue number2
DOIs
StatePublished - Jul 6 2001

Keywords

  • Ginsenosides
  • Panax ginseng

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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