Living donor liver paired exchange: A North American first

Madhukar S. Patel, Zubaida Mohamed, Anand Ghanekar, Gonzalo Sapisochin, Ian McGilvray, Blayne A. Sayed, Trevor Reichman, Markus Selzner, Jed A. Gross, Zita Galvin, Mamatha Bhat, Les Lilly, Mark Cattral, Nazia Selzner

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Paired organ exchange can be used to circumvent living donor-recipient ABO incompatibilities. Herein, we present the first case of successful liver paired exchange in North America. This 2-way swap required 4 simultaneous operations: 2 living donor hepatectomies and 2 living donor liver transplants. A nondirected anonymous living donor gift initiated this domino exchange, alleviating an ABO incompatibility in the other donor-recipient pair. With careful attention to ethical and logistical issues, paired liver exchange is a feasible option to expand the donor pool for incompatible living liver donor-recipient pairs.

Original languageEnglish (US)
Pages (from-to)400-404
Number of pages5
JournalAmerican Journal of Transplantation
Volume21
Issue number1
DOIs
StatePublished - Jan 2021
Externally publishedYes

Keywords

  • ABO incompatibility
  • clinical research/practice
  • donors and donation: living
  • donors and donation: paired exchange
  • liver transplantation/hepatology
  • liver transplantation: living donor

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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