Local harmonic motion for in vivo focused ultrasound surgery monitoring

Laura Curiel, Rajiv Chopra, Kullervo Hynynen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The present study established the feasibility of a technique for monitoring FTJS lesion formation in vivo using localized harmonic motion (LHM) measurements. Oscillatory motion was generated within tissues by induction of a periodic radiation force with a focused ultrasound (FTJS) transducer. The harmonic motion was estimated using cross-correlation of RF ultrasonic signals acquired at different instances during the motion by using a co-focal diagnostic ultrasound transducer. The technique was evaluated in vivo rabbit muscle in an MR imager for simultaneous ultrasound harmonic motion tracking and MR thermometry. The calculated maximum amplitude of the induced harmonic motion before and after the lesion formation was significantly different for all the tested motion frequencies. During the FUS exposure a drop in the maximum amplitude value was observed and a threshold value could be associated to the formation of a thermal lesion. A series of controlled sonications was performed by stopping the exposure when the threshold value in LHM amplitude was reached and the apparition of a thermal lesion was confirmed by MR imaging.

Original languageEnglish (US)
Title of host publicationProceedings - IEEE Ultrasonics Symposium
Pages1961-1964
Number of pages4
DOIs
StatePublished - 2007
Event2007 IEEE Ultrasonics Symposium, IUS - New York, NY, United States
Duration: Oct 28 2007Oct 31 2007

Other

Other2007 IEEE Ultrasonics Symposium, IUS
CountryUnited States
CityNew York, NY
Period10/28/0710/31/07

Fingerprint

Surgery
Ultrasonics
Monitoring
Transducers
Sonication
Image sensors
Muscle
Tissue
Imaging techniques
Radiation
Hot Temperature

Keywords

  • Elastography
  • FUS
  • HIFU
  • Lesion
  • Monitoring
  • Radiation force
  • Tissue ablation
  • Ultrasound

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Curiel, L., Chopra, R., & Hynynen, K. (2007). Local harmonic motion for in vivo focused ultrasound surgery monitoring. In Proceedings - IEEE Ultrasonics Symposium (pp. 1961-1964). [4410066] https://doi.org/10.1109/ULTSYM.2007.493

Local harmonic motion for in vivo focused ultrasound surgery monitoring. / Curiel, Laura; Chopra, Rajiv; Hynynen, Kullervo.

Proceedings - IEEE Ultrasonics Symposium. 2007. p. 1961-1964 4410066.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Curiel, L, Chopra, R & Hynynen, K 2007, Local harmonic motion for in vivo focused ultrasound surgery monitoring. in Proceedings - IEEE Ultrasonics Symposium., 4410066, pp. 1961-1964, 2007 IEEE Ultrasonics Symposium, IUS, New York, NY, United States, 10/28/07. https://doi.org/10.1109/ULTSYM.2007.493
Curiel L, Chopra R, Hynynen K. Local harmonic motion for in vivo focused ultrasound surgery monitoring. In Proceedings - IEEE Ultrasonics Symposium. 2007. p. 1961-1964. 4410066 https://doi.org/10.1109/ULTSYM.2007.493
Curiel, Laura ; Chopra, Rajiv ; Hynynen, Kullervo. / Local harmonic motion for in vivo focused ultrasound surgery monitoring. Proceedings - IEEE Ultrasonics Symposium. 2007. pp. 1961-1964
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