Local production of astrocytes in the cerebral cortex

W. P. Ge, J. M. Jia

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Astrocytes are the largest glial population in the mammalian brain. Astrocytes in the cerebral cortex are reportedly generated from four sources, namely radial glia, progenitors in the subventricular zone (SVZ progenitors), locally proliferating glia, and NG2 glia; it remains an open question, however, as to what extent these four cell types contribute to the substantial increase in astrocytes that occurs postnatally in the cerebral cortex. Here we summarize all possible sources of astrocytes and discuss their roles in this postnatal increase. In particular, we focus on astrocytes derived from local proliferation within the cortex.

Original languageEnglish (US)
Pages (from-to)3-9
Number of pages7
JournalNeuroscience
Volume323
DOIs
StatePublished - May 26 2016

Keywords

  • Astrocyte
  • Cerebral cortex
  • NG2 glia
  • Proliferation
  • Radial glia
  • SVZ

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Local production of astrocytes in the cerebral cortex'. Together they form a unique fingerprint.

  • Cite this