Localization of acetylated histone H4 in the macronucleus of Euplotes

Donald E. Olins; Ada L. Olins; Adria Herrmann; Rueyling Lin; C. David Allis; Michel Robert-Nicoud

doi:10.1007/BF00337516

Localization of acetylated histone H4 in the macronucleus of Euplotes

Donald E. Olins, Ada L. Olins, Adria Herrmann, Rueyling Lin, C. David Allis, Michel Robert-Nicoud

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10 Scopus citations

Abstract

Antisera specific to acetylated and unacetylated N-terminal domains of histone H4 were employed to map the spatial distribution of exposed antigenic determinants in the macronucleus of Euplotes eurystomus. Sites of putative transcription-related acetylation appear to reside in the regions between condensed chromatin granules and disappear during chromatin restructuring in the forward zone of replication bands. Coincident with synthesis of newly replicated chromatin, the specific antisera reveal a resumption of exposed sites of H4 acetylation in the rear zone of replication bands.

Original language	English (US)
Pages (from-to)	377-385
Number of pages	9
Journal	Chromosoma
Volume	100
Issue number	6
DOIs	https://doi.org/10.1007/BF00337516
State	Published - Jul 1991

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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title = "Localization of acetylated histone H4 in the macronucleus of Euplotes",

abstract = "Antisera specific to acetylated and unacetylated N-terminal domains of histone H4 were employed to map the spatial distribution of exposed antigenic determinants in the macronucleus of Euplotes eurystomus. Sites of putative transcription-related acetylation appear to reside in the regions between condensed chromatin granules and disappear during chromatin restructuring in the forward zone of replication bands. Coincident with synthesis of newly replicated chromatin, the specific antisera reveal a resumption of exposed sites of H4 acetylation in the rear zone of replication bands.",

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AU - Olins, Donald E.

AU - Olins, Ada L.

AU - Herrmann, Adria

AU - Lin, Rueyling

AU - David Allis, C.

AU - Robert-Nicoud, Michel

PY - 1991/7

Y1 - 1991/7

N2 - Antisera specific to acetylated and unacetylated N-terminal domains of histone H4 were employed to map the spatial distribution of exposed antigenic determinants in the macronucleus of Euplotes eurystomus. Sites of putative transcription-related acetylation appear to reside in the regions between condensed chromatin granules and disappear during chromatin restructuring in the forward zone of replication bands. Coincident with synthesis of newly replicated chromatin, the specific antisera reveal a resumption of exposed sites of H4 acetylation in the rear zone of replication bands.

AB - Antisera specific to acetylated and unacetylated N-terminal domains of histone H4 were employed to map the spatial distribution of exposed antigenic determinants in the macronucleus of Euplotes eurystomus. Sites of putative transcription-related acetylation appear to reside in the regions between condensed chromatin granules and disappear during chromatin restructuring in the forward zone of replication bands. Coincident with synthesis of newly replicated chromatin, the specific antisera reveal a resumption of exposed sites of H4 acetylation in the rear zone of replication bands.

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JO - Chromosoma

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ER -

Localization of acetylated histone H4 in the macronucleus of Euplotes

Abstract

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