Long-term efficacy of fulguration of trigonitis for recurrent urinary tract infections in women

Syed A. Hussain, Feras Alhalabi, Philippe E. Zimmern

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12 Scopus citations

Abstract

Objective: Women with a longstanding history of recurrent urinary tract infections (RUTIs) represent a challenging population because of gradual development of antibiotic resistance and frequent antibiotic allergies. We report on the long-term results of women with RUTIs and trigonitis who were treated using endoscopic fulguration and were prospectively followed. Materials and methods: Following institutional review board approval, charts of non-neurogenic women with RUTIs (defined as ≥3 UTIs/y), no voiding dysfunction or incontinence, and normal upper tracts by imaging, who underwent cystoscopy with fulguration of trigonitis (CFT) under anesthesia with 1 year minimum follow up after CFT, were reviewed. Trigonitis was defined as a condition of inflammation of the trigone region of the bladder. The primary outcome was complete resolution of trigonitis based on follow-up office cystoscopy 6 months after CFT. The secondary outcome was the total number of antibiotic courses (AC) prescribed for UTI-related symptoms and/or positive urine cultures (PUC) following CFT. We hypothesized that patients with complete trigonitis resolution after CFT fared best. Results: From 2004 to 2008, 33 women met the inclusion criteria with a mean follow up of 48 ± 19 months (range, 14-82 months). Resolution of trigonitis at 6 months was noted in 25 (76%) patients. This group averaged 0.51 ± 0.5 total AC and/or PUC/y compared with 2.03 ± 1.1 total AC and/or PUC/y for women with persistent trigonitis following CFT (p = 0.006). Conclusion: Patients with resolved trigonitis at 6 months after CFT did best; however, both groups benefited from the procedure over time.

Original languageEnglish (US)
Pages (from-to)197-201
Number of pages5
JournalUrological Science
Volume26
Issue number3
DOIs
Publication statusPublished - Sep 1 2015

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Keywords

  • Female
  • Fulguration
  • Recurrent urinary tract infections
  • Trigonitis

ASJC Scopus subject areas

  • Urology

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