TY - JOUR
T1 - Long-Term Functional Recovery, Quality of Life, and Pregnancy After Solid Organ Transplantation
AU - Rao, Swati
AU - Ghanta, Mythili
AU - Moritz, Michael J.
AU - Constantinescu, Serban
N1 - Funding Information:
Disclosure Statement: The National Transplantation Pregnancy Registry is supported by grants from Astellas Pharma US , Pfizer , and Bristol-Myers Squibb Company .
Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - This article reviews the salient features of functional recovery, health-related quality of life (HR-QOL), and reproductive health, with special emphasis on pregnancy outcomes in kidney and liver recipients. Transplantation results in improved functional status and HR-QOL. Addressing factors that limit the optimal rehabilitation of transplant recipients can improve transplant outcomes. After successful transplantation, there is a rapid return of fertility, warranting counseling regarding contraception. Practitioners should be aware of the teratogenic potential of mycophenolic acid products. Posttransplant pregnancies are high risk, with increased incidences of hypertension, preeclampsia, and prematurity. Most pregnancies in kidney and liver recipients have successful maternal and newborn outcomes.
AB - This article reviews the salient features of functional recovery, health-related quality of life (HR-QOL), and reproductive health, with special emphasis on pregnancy outcomes in kidney and liver recipients. Transplantation results in improved functional status and HR-QOL. Addressing factors that limit the optimal rehabilitation of transplant recipients can improve transplant outcomes. After successful transplantation, there is a rapid return of fertility, warranting counseling regarding contraception. Practitioners should be aware of the teratogenic potential of mycophenolic acid products. Posttransplant pregnancies are high risk, with increased incidences of hypertension, preeclampsia, and prematurity. Most pregnancies in kidney and liver recipients have successful maternal and newborn outcomes.
KW - Functional recovery
KW - Kidney transplantation
KW - Liver transplantation
KW - Pregnancy
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84961221224&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84961221224&partnerID=8YFLogxK
U2 - 10.1016/j.mcna.2016.01.010
DO - 10.1016/j.mcna.2016.01.010
M3 - Review article
C2 - 27095649
AN - SCOPUS:84961221224
SN - 0025-7125
VL - 100
SP - 613
EP - 629
JO - Medical Clinics of North America
JF - Medical Clinics of North America
IS - 3
ER -